Salbutamol Aerosol

Salbutamol is called a bronchodilator medicine because it dilates (widens) your airways. It works by opening up the air passages in your lungs so that air can flow into your lungs more freely.

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Details

Salbutamol aerosol

Description

Albuterol Inhalation Aerosol is a pressurized metered-dose aerosol unit for oral inhalation.

Introduction

Product Name:Salbutamol Aerosol,Albuterol Inhalation

Nombre del Producto: Salbutamol aerosol

Specification: 100mcg

Package: 200puffs, 20mg, CFC/CFC free

Standard: BP


This helps to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as coughing, wheezing and feeling breathless.

 

Indications

Salbutamol is typically used to treat bronchospasm (due to any cause, allergen asthma or exercise-induced), as well as chronic obstructive pulmonary disease.

As a β2-agonist, salbutamol also finds use in obstetrics. Intravenous salbutamol can be used as a tocolytic to relax the uterine smooth muscle to delay premature labor.

Salbutamol has been used to treat acute hyperkalemia, as it stimulates potassium flow into cells thus lowering the level in the blood.

Salbutamol has also been tested in a trial aimed at treatment of spinal muscular atrophy, where it appears to show modest benefits. The drug is speculated to modulate the alternative splicing of the SMN2 gene, increasing the amount of the SMN protein whose deficiency is regarded as the root cause of the disease.

Other potential uses include in cystic fibrosis,and subtypes of congenital myasthenic syndrome associated with mutations in Dok-7.

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Dosage and administration

For treatment of acute episodes of bronchospasm or prevention of asthmatic symptoms, the usual dosage for adults and pediatric patients 4 years and older is two inhalations repeated every four to six hours; in some patients, one inhalation every four hours may be sufficient. More frequent administration or a larger number of inhalations are not recommended. It is recommended to "test spray" Albuterol Inhalation Aerosol into the air before using for the first time and in cases where the aerosol has not been used for a prolonged period of time.

 

The use of Albuterol Inhalation Aerosol can be continued as medically indicated to control recurring bouts of bronchospasm. During this time most patients gain optimal benefit from regular use of the inhaler. Safe usage for periods extending over several years has been documented.

 

Side Effect 

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; headache; nausea; nervousness; runny or stuffy nose; sore or dry throat; tremor; trouble sleeping; unusual taste in mouth; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); chest pain; decreased coordination; fast breathing; fast heartbeat; new or worsened breathing problems (eg, shortness of breath, wheezing); pounding in the chest; severe or persistent headache or dizziness; severe or persistent nausea or vomiting; sluggishness; symptoms of low blood potassium levels (eg, irregular heartbeat; muscle pain, weakness, or cramping); voice changes..

 

Contraindications

Albuterol Inhalation Aerosol is contraindicated in patients with a history of hypersensitivity to albuterol or any of its components.

 

Precautions

Albuterol, as with all sympathomimetic amines, should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias, and hypertension; in patients with convulsive disorders, hyperthyroidism, or diabetes mellitus; and in patients who are unusually responsive to sympathomimetic amines. Clinically significant changes in systolic and diastolic blood pressure have been seen in individual patients and could be expected to occur in some patients after use of any beta-adrenergic bronchodilator.

 

Large doses of intravenous albuterol have been reported to aggravate preexisting diabetes mellitus and ketoacidosis. As with other beta-agonists, albuterol may produce significant hypokalemia in some patients, possibly through intracellular shunting, which has the potential to produce adverse cardiovascular effects. The decrease is usually transient, not requiring supplementation.

 

Although there have been no reports concerning the use of Albuterol Inhalation Aerosol during labor and delivery, it has been reported that high doses of albuterol administered intravenously inhibit uterine contractions. Although this effect is extremely unlikely as a consequence of aerosol use, it should be kept in mind.

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