Ipratropium Bromide Aerosol

Ipratropium Bromide Aerosol

Ipratropium bromide aerosol is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

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Ipratropium bromide aerosol

Ipratropium bromide aerosol 

The active ingredient in Ipratropium bromide aerosol is ipratropium bromide. It is an anticholinergic bronchodilator chemically described as 8azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-,bromide monohydrate, (3-endo, 8-syn)-: a synthetic quaternary ammonium compound, chemically related to atropine.

Ipratropium bromide aerosol is used for:

Nombre del Producto : Bromuro de ipatropio aerosol

Specification: 120mcg

Package: 120mcg/dosis x 200dosis

Standard: BP

Dosage and Administration:

The usual starting dose is two inhalations four times a day. Patients may take additional inhalations as required; however, the total number of inhalations should not exceed 12 in 24 hours.

It is a solution aerosol that does not require shaking. However, as with any other metered-dose inhaler, some coordination is required between actuating the canister and inhaling the medication.

Patients should “prime” or actuate it before using for the first time by releasing 2 test sprays into the air away from the face. In cases where the inhaler has not been used for more than 3 days, prime the inhaler again by releasing 2 test sprays into the air away from the face. Patients should avoid spraying it into their eyes.

Each inhaler provides sufficient medication for 200 actuations. The inhaler should be discarded after the labeled number of actuations has been used. The amount of medication in each actuation cannot be assured after this point, even though the canister is not completely empty.


Side Effects:

The following adverse reactions are described, or described in greater detail, in other sections:

·Hypersensitivity reactions, including anaphylaxis

·Paradoxical bronchospasm

·Ocular effects

·Urinary retention

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in patients.


Drug Interactions:

Ipratropium bromide aerosol has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroids commonly used in the treatment of chronic obstructive pulmonary disease. With the exception of albuterol, there are no formal studies fully evaluating the interaction effects of Ipratropium bromide aerosol and these drugs with respect to safety and effectiveness.


Anticholinergic Agents

There is potential for an additive interaction with concomitantly used anticholinergic medications. Therefore, avoid coadministration of Ipratropium bromide aerosol with other anticholinergic-containing drugs as this may lead to an increase in anticholinergic adverse effects


Overdose:

Acute overdose by inhalation is unlikely since ipratropium bromide is not well absorbed systemically after inhalation or oral administration


Contraindications

It is contraindicated in the following conditions.

Hypersensitivity to ipratropium bromide or other ATROVENT HFA components

Hypersensitivity to atropine or any of its derivatives 


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We are considered as one of the leading manufacturers and suppliers of ipratropium bromide aerosol. With the aid of our technologically advanced manufacturing section, we are able to offer customers ipratropium bromide aerosol products which are tested on various quality parameters in order to supply flawless range at the customers' end.

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