Product Name:Iohexol injection
Nombre del Producto:Iohexol inyección
Specification: 50ml 15g (I) 100ml 30g (I) 100ml 35g (I)
Standard: USP & BP Currently
Contrast agents are used to create a clear picture of the different parts of the body during certain medical procedures such as CT scans and angiography.
Iohexol, N,N´ - Bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)-acetamido]-2,4, 6-triiodoisophthalamide, is a nonionic, water-soluble radiographic contrast medium with a molecular weight of 821.14 (iodine content 46.36%). In aqueous solution each triiodinated molecule remains undissociated. The chemical structure is:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For iohexol, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to iohexol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of iohexol in children. Some pediatric patients with certain medical conditions may have more unwanted side effects which may require caution in patients receiving iohexol.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of iohexol in the elderly. However, elderly patients are more likely to have unwanted side effects which may require caution in patients receiving iohexol.
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking iohexol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using iohexol with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using iohexol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of iohexol. Make sure you tell your doctor if you have any other medical problems, especially:
Alcohol abuse or
Heart or blood vessel disease or
Multiple sclerosis or
Seizures or epilepsy, history of—Iohexol injection should be used with caution in these patients.
Allergies or hypersensitivities, or
Allergic rhinitis (hay fever) or
Allergy to a contrast agent, history of or
Allergy to food or
Allergy to iodine or
Asthma—Use with caution. May increase risk of having allergic reactions.
Anuria (not able to pass urine) or
Blood vessel disease, severe or
Congestive heart failure or
Diabetic nephropathy or
Kidney disease or
Multiple myeloma (cancer of plasma cells) or
Paraproteinemia (high amount of paraprotein in the blood)—May increase risk of having kidney failure.
Blood clotting problems (eg, thrombosis) or
Heart or blood vessel disease (eg, arteriosclerosis) or
Hypertension (high blood pressure) or
Hyperthyroidism (overactive thyroid) or
Kidney disease, severe or
Liver disease or
Pheochromocytoma (adrenal problem) or
Sickle cell anemia (inherited blood disorder)—Use with caution. May make these conditions worse.
Homocystinuria (genetic disease)—Patients with this condition should avoid undergoing angiography because of the increased risk of having blood clotting problems.
Infection—Iohexol injection should not be given for myelography in patients with this condition.
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