L-Asparaginase For Injection

L-Asparaginase For Injection

Asparaginase is used with or without other anticancer (chemotherapy) drugs to treat acute lymphocytic leukemia (ALL). It works by starving tumor cells of needed nutrients and slowing tumor cell growth.


L-Asparaginase for injection

L-Asparaginase for injection 10000iu 

Nombre del Producto: L-Asparraguinasa para inyección

Specification: 10000iu

Package: 1vial/box

Standard: Internal standard 

Uses For asparaginase

Asparaginase injection is used together with other medicines to treat acute lymphoblastic leukemia (ALL), a cancer of the blood.

Asparaginase belongs to the group of medicines known as enzymes. All cells need a chemical called asparagine to stay alive. Normal cells can make this chemical, but cancer cells cannot. Asparaginase breaks down asparagine in the body. Since the cancer cells cannot make more asparagine, they die.

asparaginase is to be given only by or under the immediate supervision of your doctor.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, asparaginase is used in certain patients with the following condition:

Acute myeloid leukemia (cancer of the blood).

Before Usingasparaginase

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For asparaginase, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to asparaginase or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of asparaginase injection in children.


Although appropriate studies on the relationship of age to the effects of asparaginase injection have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.


Pregnancy Explanation Category

All Trimesters CAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using asparaginase.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving asparaginase, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using asparaginase with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Rotavirus Vaccine, Live

Using asparaginase with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Adenovirus Vaccine Type 4, Live

Adenovirus Vaccine Type 7, Live

Bacillus of Calmette and Guerin Vaccine, Live

Influenza Virus Vaccine, Live

Measles Virus Vaccine, Live


Mumps Virus Vaccine, Live



Rubella Virus Vaccine, Live

Smallpox Vaccine

Typhoid Vaccine

Varicella Virus Vaccine


Vincristine Sulfate Liposome

Yellow Fever Vaccine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of asparaginase. Make sure you tell your doctor if you have any other medical problems, especially:

Bleeding problems or

Blood clotting problems or

Diabetes or

Hyperglycemia (high blood sugar) or

Liver disease or

Pancreatitis (inflamed pancreas)—Use with caution. May make these conditions worse.

Bleeding problems due to asparaginase, history of or

Blood clotting problems due to asparaginase, history of or

Pancreatitis (inflamed pancreas) due to asparaginase, history of—Should not be given to patients with these conditions.

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