Somatropin (rDNA origin) injection
Product Name：Somatropin (rDNA origin) injection, Jintropin,Genotropin, Humatrope, Norditropin, Nutropin, Serostim, Zorbtive
Nombre del Producto: Somatropina (origen rDNA) inyección
Specification: 15iu/5mg, 30iu/10mg, 3ml catridge
Package: 3ml catridge
Pediatric growth hormone deficiency
Adult Growth hormone deficiency
Dosage and administration
* The dose of administration should be individual for each patient. For growth-promotion purpose in children, the recommended dose is 0.1-0.15 IU/kg/day, once per day, subcutaneous injection. The period of treatment is from 3 months to 3 years. Or follow your physicians prescription.
*For severe burn patients, a daily dose of 0.2-0.4I U/kg subcutaneous injection is recommended. The period of treatment is about 2 weeks.
*The dose might require adjustment individually for human GH replacement therapy. Pls follow your physicians instructions.
Common adverse reactions reported in adult and pediatric patients taking somatropin include injection site reactions. Additional common adverse reactions in adults include edema, arthralgia, and carpal tunnel syndrome.
Acute critical illness
Prader-Willi syndrome (PWS) in children
Somatropin inhibits 11ß-hydroxysteroid dehydrogenase type 1 (11ßHSD-1) in adipose/hepatic tissue and may significantly impact the metabolism of cortisol and cortisone. As a consequence, in patients treated with somatropin, previously undiagnosed central (secondary) hypoadrenalism may be unmasked, requiring glucocorticoid replacement therapy
Careful monitoring is advisable when somatropin is administered in combination with insulin and/or other hypoglycemic agents, other drugs metabolized by CYP450 liver enzymes (eg, hydrocortisone or other corticosteroids, sex steroids, anticonvulsants, cyclosporine), or other hormone replacement therapy