Furosemide Injection

Furosemide Injection

Cardiac oedema: All forms of cardiac oedema in conjunction with adequate glycoside therapy. Ascites due to cirrhosis of the liver, mechanical obstruction or cardiac failure. Renal oedema (in nephrotic syndrome usually in conjunction with ACTH or corticosteroids). Pulmonary oedema. Cerebral oedema.

Details

Furosemide injection

Indication

Product Name: Furosemide Injection

Nombre del Producto:Furosemida solución Inyectable

Specification: 20mg/2ml

Package: 10amps/box, 50amps/box, 100amps/box

Standard: BP & USP & CP


Forced diuresis e.g. management of barbiturate poisoning.

Burns: to reduce local oedema and to prevent oliguria from progressing to complete anuria. 


Contra-indications

Patients who are hypersensitive to furosemide or sulphonamides.

Increased azotaemia and oliguria occurring during treatment of severe progressive renal disease – the drug should be discontinued. In hepatic coma and in states of electrolyte depletion, hypovolaemia and hypotension, therapy with Furosemide Injection should not be instituted until the basic condition is corrected or improved.

Lactating women.

 

Warnings

Fluid and electrolyte imbalance should be monitored during therapy.

 

Dosage and directions for use

Intravenous or intramuscular administration of furosemide is indicated in all cases where intestinal absorption is impaired or prompt diuresis is required. The rapid and powerful effect produced by intravenous injection may result in a transitory fall in plasma volume.

Intravenous injection should be given slowly (over 1 to 2 minutes).

The recommended adult dose by this route is 20 to 40 mg, repeated if necessary after not less than 2 hours. The usual pediatric dose is 1 mg/kg.

Pulmonary oedema: Initial dose 40 mg intravenously. If necessary, the injection may be repeated after approximately 60 to 90 minutes.

 

Side-effects and special precaustions

With parenteral use of furosemide in high doses reversible deafness and tinnitus have been reported when the infusion is faster than 4 mg per minute. Permanent deafness may develop in patients with impaired renal function.

Various forms of skin reactions including rashes, urticaria, exfoliative dermatitis, paraesthesia, pruritis, purpura, photosensitivity and erythema multiforme may occur.

Nausea, vomiting, diarrhoea, blurred vision, dizziness, headache, pancreatitis, muscle spasm, cramps, hypotension and allergic reactions may occur.

Furosemide should be used with care in patients with prostatic hypertrophy or impairment of micturition.

Anaemia, leucopenia, agranulocytosis, aplastic anaemia and thrombocytopenia (with purpura) may occur.

 

Storage instructions

Store below 25°C. Protect from light. Keep out of reach of children.

 

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