Levofloxacin Tablet

Levofloxacin Tablet

Product name:Levofloxacin film coated tablet

Package: 10tablets/blister

Specification: 500mg

Certification:GMP

Standard:CP/USP

Details

Product name:Levofloxacin film coated tablet

Package: 10tablets/blister

Specification: 500mg

Certification:GMP

Standard:CP/USP

OEM: Available

Shelf Life: 3 Years

 

Product Details

Ingredients

This product is mainly composed of levofloxacin.

Chemical Name: (―)-(S)-3-Methyl-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo Substitution -7H-Pyridino[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid hemihydrate.

Chemical Structure:

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Molecular Formula: C18H20FN3O4·1/2(H2O)

Molecular weight: 370.38


Character

This product is light pink oval film piece, remove the film clothing was white to pale yellow.


Indications

This product is suitable for the following mild to moderate infections caused by sensitive bacteria:

1. Respiratory infections: acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia;

2. Urinary system infections: acute pyelonephritis, complicated urinary tract infections;

3. Reproductive system infections: prostatitis, epididymitis, uterine cavity infection, uterine attachment inflammation, pelvic inflammatory disease (combination of metronidazole if anaerobic infection is suspected);

4. skin and soft tissue infections: infectious impetigo, cellulitis, lymphatic (node) inflammation, subcutaneous abscess, perianal abscess, etc.;

5. Intestinal infections: bacterial dysentery, infectious enteritis, Salmonella enteritis, typhoid and paratyphoid;

6. Other infections: trauma, burns and wound infections after surgery, intra-abdominal infections (metronidazole if necessary), mastitis, cholecystitis, cholangitis, bone and joint infections, and ENT infections.


Specification

0.5g


Dosage

Oral, adult once 0.5g (1), once a day.


Adverse reactions

Adverse reactions may occur during medication:

1. Digestive system: Sometimes nausea, vomiting, abdominal discomfort, diarrhea, anorexia, abdominal pain, indigestion, etc.

2. Allergies: occasional edema, urticaria, fever, photosensitivity and sometimes rash, itching, erythema and other symptoms;

3. Nervous system: occasional tremor, numbness, visual abnormalities, tinnitus, hallucinations, lethargy, and sometimes insomnia, dizziness, headache and other symptoms;

4. Kidney: Occasionally blood urea nitrogen rises;

5. Liver: Abnormal liver function may occur, such as increased blood aminotransferase, increased serum total bilirubin, etc.;

6. Blood: sometimes anemia, leukopenia, thrombocytopenia, and eosinophilia increase;

The incidence of adverse reactions above is between 0.1% and 5%. Occasional fatigue, fever, palpitations, abnormal taste and so on. Can generally tolerate, disappear quickly after the end of treatment. Very rare pancytopenia, toxic epidermal necrolysis, erythema multiforme, fulminant hepatitis. If abnormalities are found, observe them and if necessary, stop using drugs and perform proper disposal.


Contraindication

Allergy to quinolones, pregnant women and nursing women, disabled patients under the age of 18.


Precautions

1. Renal insufficiency should be reduced or extended dosing interval, severe renal insufficiency caution.

2. Patients with central nervous system disease and history of epilepsy should be used with caution.

3. Quinolones can still cause rare phototoxic reactions (incidence <0.1%). In the treatment of this product should avoid excessive sun exposure and artificial UV. If photosensitivity reaction or skin damage occurs, this product should be disabled.

4. If allergies occur, the drug should be discontinued immediately, and the following drugs or methods should be used according to the specific clinical conditions: Adrenaline and other rescue measures, including oxygen inhalation, intravenous infusion, antihistamines, corticosteroids and so on.

5. Quinolone drugs can still cause rare shock, allergic reactions, toxic epidermal necrosis, acute renal insufficiency, jaundice, agranulocytosis, leukopenia, hemolytic anemia, interstitial pneumonia, pseudomembranous colitis and other partners Severe colitis with bloody stools.

6. In addition, reports of rhabdomyolysis, hypoglycemia, Achilles tendinitis, rupture of Achilles tendon, mental disorders, and allergic vasculitis occur after drug use. If any of these symptoms occurs, the drug should be discontinued immediately and appropriate treatment must be performed. Until the symptoms disappear.

7. Levofloxacin cannot be effectively eliminated by hemodialysis or peritoneal dialysis.


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