Product name: Ampicillin sodium and Sulbactam sodium for Injection
Shelf Life: 3 Years
Ampicillin sodium and Sulbactam sodium for Injection
This product is suitable for the production of β-lactamase Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, Staphylococcus, Escherichia coli, Klebsiella, Proteus mirabilis, Bacteroides fragilis The respiratory tract, hepatobiliary system, urinary system, and skin and soft tissue infections caused by Acinetobacter spp., Enterococcus spp., etc., are particularly suitable for mixed infections of aerobic and anaerobic bacteria, particularly abdominal infections and pelvic infections. It is also valid for the above infection caused by ampicillin-sensitive bacteria. This product is not suitable for infections caused by Pseudomonas aeruginosa, Citrobacter, Providencia, Enterobacter, Morgenella, and Serratia.
Deep intramuscular injection, intravenous injection or intravenous drip. Dissolve each dose in 50 to 100 ml of the appropriate dilution solution intravenously within 15 to 30 minutes.
Adults 1.5 to 3g (including ampicillin and sulbactam) once every 6 hours. The daily dose for intramuscular injection does not exceed 6 g and the daily dose for intravenous administration does not exceed 12 g (the maximum daily dose of sulbactam does not exceed 4 g).
Children were dosed on a daily basis at a dose of 100 to 200 mg/kg body weight.
According to data from 11764 cases in the United States and Europe, less than 10% of adverse reactions occurred, of which only 0.7% stopped due to serious adverse reactions. The pain at the injection site was about 3.6%, diarrhea, nausea and other reactions occurred occasionally, and the incidence of skin rash was 1% to 6%. Occasionally transient increase in serum aminotransferase. Exfoliative dermatitis and anaphylactic shock occur in a very few cases.
1. Allergic to penicillin antibiotics are prohibited.
2. Patients with infectious mononucleosis, cytomegalovirus infection, lymphocytic leukemia, lymphoma, etc. are prone to skin rashes, so they should not be used.
1. Penicillin skin test must be done before the use of the drug, and the positive is prohibited.
2. Cross-allergy: Allergic to a penicillin antibiotic may also be allergic to other penicillin antibiotics. May also be allergic to penicillamine or cephalosporins.
3. The following conditions should be used with caution: Those with a history of allergic diseases such as asthma, eczema, hay fever, and urticaria.
4. Renal dysfunction, adjust medication based on plasma creatinine clearance.